We are looking for a motivated scientist who enjoys working in a multidisciplinary team. The main task will be the development of bio-assays for characterisation of vaccines that are produced with the PER.C6® technology. Assay development activities will mainly focus on assays that measure vaccine potency and vaccine purity. These include different formats, but will have a focus on ELISA, (q)PCR and cell culture-based assay systems.
The scientist independently hypothesises, designs and reports assay development or optimisation activities with hands-on involvement. Further responsibilities will be to leverage the work of project members to meet project checkpoints and accomplish team objectives on time and within budget.
The Molecular Bioassay group is part of the Analytical Development (AD) group and is responsible for developing methods that are employed to analyse and characterise virus based vaccines. Product analysis includes tests for quantity, potency, purity, and identity, but also detailed structural characterisation of vaccines.
The Analytical Development group, which is part of the pharmaceutical and analytical department, has a pivotal role between the regulatory authorities quality unit and process development. In addition, the AD department supports other departments (formulation, USP and DSP development) by routine sample analysis. Within AD, the scientist will be working in the molecular and bioassay (MBA) group, which is responsible for the development of new bioassays in order to characterise virus based vaccines.
- A suitable candidate will have a Ph.D. degree (or equivalent) with 2-3 years post-doctoral experience or a minimum of 12 years of experience performing progressively advanced duties beyond a B.S. degree in a relevant field of cell-based assays, molecular biology, cell biology, or life sciences and is familiar with techniques as ELISA, qPCR, cell culture, virus culture.
- Open to MSc. level provided you have at least 2-3 years relevant pharma and company experience.
- Late stage highly preferred
- Experience in working in industry or assay development or GMP is considered advantageous.
If this position is something that you want to do, and if you believe you have the right qualifications and experience required for the role, please do not hesitate and send us an e-mail with your most recent CV and short motivation letter to: j.vanbaalen(@)progressive-nl.com